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Title: 2,5-Dimethoxy-4-propylamphetamine  
Author: World Heritage Encyclopedia
Language: English
Subject: DMMDA, Methallylescaline, 2,5-Dimethoxy-4-fluoroamphetamine, Jimscaline, Macromerine
Collection: 2C (Psychedelics), Amphetamines, Designer Drugs, Substituted Amphetamines
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Legal status
CAS number  N
53581-55-8 (hydrochloride)
ATC code ?
ChemSpider  YesY
Synonyms 2,5-dimethoxy-4-propylamphetamine
Chemical data
Formula C14H23NO2 
Mol. mass 237.34 g/mol

2,5-Dimethoxy-4-propylamphetamine (DOPR) is a synthesized by Alexander Shulgin, and was described in his book PiHKAL (Phenethylamines i Have Known And Loved). Shulgin described DOPR is a "heavy duty psychedelic", complete with alterations of the thought process and visual distortion.[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of DOPR.

The alternative structural isomer DOIP, with a 4-isopropyl substitution, is also known but is around ten times weaker than DOPR, with an active dose of some 20-30mg (as compared to 2-5mg for DOPR).[1]

Structure of DOIP

See also


  1. ^ a b Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. United States: Transform Press. p. 978.  

External links

  • PiHKALDOPR Entry in
  • DOPR Entry in PiHKAL • info

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