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Title: Buflomedil  
Author: World Heritage Encyclopedia
Language: English
Subject: ATC code C04
Publisher: World Heritage Encyclopedia


CAS number 55837-25-7 YesY
PubChem 2467
ChemSpider 2373 YesY
ATC code AX20
Jmol-3D images Image 1
Molecular formula C17H25NO4
Molar mass 307.38 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Buflomedil is a vasoactive drug used to treat claudication or the symptoms of peripheral arterial disease. It is currently not approved by the Food and Drug Administration (FDA) for use in the United States. Currently available as trade name tablet Loftyl


This drug might be suspended from marketing in the European Union, because of concerns about severe neurological and cardiac toxicity.[1][2] In its press release dated 17 November 2011 EMA suggested that doctors "should stop using buflomedil and consider alternative treatment options".

Various adverse effects have been reported to the FDA.[3]


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