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Ebalzotan

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Title: Ebalzotan  
Author: World Heritage Encyclopedia
Language: English
Subject: Robalzotan, 5-HT1A receptor, PNU-142633, E-55888, LP-44
Collection: Amines, Carboxamides, Chromanes
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Ebalzotan

Ebalzotan
Systematic (IUPAC) name
(3R)-N-(propan-2-yl)-3-[propan-2-yl(propyl)amino]-3,4-dihydro-2H-chromene-5-carboxamide
Clinical data
Legal status
  • Uncontrolled
Routes Oral
Identifiers
CAS number
ATC code None
PubChem
ChemSpider
UNII  YesY
Chemical data
Formula C19H30N2O2 
Mol. mass 318.45 g/mol

Ebalzotan (NAE-086) is a selective 5-HT1A receptor agonist.[1][2] It was under development as an antidepressant and anxiolytic agent but produced undesirable side effects in phase I clinical trials and was subsequently discontinued.[1][2]

See also

References

  1. ^ a b Tamim Braish; Gadamasetti, Kumar G. (2008). Process chemistry in the pharmaceutical industry, volume 2 challenges in an ever changing climate. Boca Raton: CRC Press.  
  2. ^ a b Weaver, Donald F.; Nogrady, Thomas; Nogrady, Th (2005). Medicinal chemistry a molecular and biochemical approach. Oxford [Oxfordshire]: Oxford University Press.  


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