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Title: Fluacizine  
Author: World Heritage Encyclopedia
Language: English
Subject: Phenothiazines, List of compounds with carbon number 20, Antidepressants, Butaclamol, Acetophenazine
Publisher: World Heritage Encyclopedia


Skeletal formula of fluacizine
Space-filling model of the fluacizine molecule
Systematic (IUPAC) name
Clinical data
Legal status
  • (Prescription only)
Routes of
Oral, IM
CAS Registry Number
ATC code None
PubChem CID:
ChemSpider  Y
Chemical data
Formula C20H21F3N2OS
Molecular mass 394.455 g/mol

Fluacizine (Phthorazisin), also known as fluoracizine and ftoracizine, is a phenothiazine derivative which, unlike most other phenothiazines which are used as antipsychotics, is an antidepressant with sedative effects that was marketed in Russia.[1][2][3][4] It is known to act as a norepinephrine reuptake inhibitor, antihistamine, and anticholinergic.[1][5][6][7]

See also


  1. ^ a b Author Unknown (1972). Ann Reports Medicinal Chem V7 (v. 7). Boston: Academic Press.  
  2. ^ Vikhlyaev YI, Zherdev VP, Ul'yanova OV (November 1974). "Distribution and action of fluacizine during prolonged administration". Bulletin of Experimental Biology and Medicine 77 (5): 524–6.  
  3. ^ David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC.  
  4. ^ O'Neil, Maryadele J. (2001). The Merck index: an encyclopedia of chemicals, drugs, and biologicals. Rahway, NJ: Merck Research Laboratories.  
  5. ^ Arefolov VA, Panasyuk LV, Raevskii KS, Kostyukov VI (September 1974). "Effect of fluacizine on the uptake of exogenous noradrenalin by the isolated rat vas deferens". Bulletin of Experimental Biology and Medicine 77 (3): 295–7.  
  6. ^ Arefolov VA, Panasyuk LV (November 1974). "Effect of fluacizine on the uptake of exogenous noradrenalin". Bulletin of Experimental Biology and Medicine 77 (5): 520–3.  
  7. ^ Arefolov VA, Panasiuk LV, Firsov VK (1975). "[Neuromediator content in the synaptic vesicles of rat adrenergic nerves in some pharmacological actions]". Farmakologiia I Toksikologiia (in Russian) 38 (3): 285–9.  

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