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Viqualine

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Title: Viqualine  
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Subject: RS-56812, BRL-54443, 6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide, PNU-22394, SB-215505
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Viqualine

Viqualine
Systematic (IUPAC) name
4-[3-[(3R,4R)-3-ethenylpiperidin-4-yl]propyl]-6-methoxyquinoline
Clinical data
Legal status
?
Identifiers
CAS number
ATC code ?
PubChem
ChemSpider
UNII  YesY
ChEMBL
Chemical data
Formula C20H26N2O 
Mol. mass 310.432 g/mol
 YesY   

Viqualine (PK-5078) is a psychoactive drug and research chemical of the quinoline chemical class that possesses antidepressant and anxiolytic properties.[1] It acts as a selective serotonin releasing agent (SSRA).[2] It has mainly been researched as a potential treatment for alcoholism.[3][4]

References

  1. ^ Faravelli C, Albanesi G, Sessarego A (1988). "Viqualine in resistant depression: a double-blind, placebo-controlled trial". Neuropsychobiology 20 (2): 78–81.  
  2. ^ Le Fur G, Imbault F, Mitrani N, Marquis F, Renault C, Dubroeucq MC, Gueremy C, Uzan A (February 1984). "The 5-hydroxytryptamine-releasing properties of two epimer quinoline derivatives". Neuropharmacology 23 (2A): 169–73.  
  3. ^ Naranjo CA, Sellers EM (1989). "Serotonin uptake inhibitors attenuate ethanol intake in problem drinkers". Recent Developments in Alcoholism : an Official Publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism 7: 255–66.  
  4. ^ Naranjo CA, Sullivan JT, Kadlec KE, Woodley-Remus DV, Kennedy G, Sellers EM (September 1989). "Differential effects of viqualine on alcohol intake and other consummatory behaviors". Clinical Pharmacology and Therapeutics 46 (3): 301–9.  



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