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2,2,2-Trichloroethanol

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Title: 2,2,2-Trichloroethanol  
Author: World Heritage Encyclopedia
Language: English
Subject: Alcoholic beverage, Ethanol, Dextromethorphan, Phencyclamine, N-Ethylnorketamine
Collection: Alcohols, Gabaa Receptor Positive Allosteric Modulators, Glycine Receptor Agonists, Halohydrins, Organochlorides, Sedatives
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2,2,2-Trichloroethanol

2,2,2-Trichloroethanol
2,2,2-Trichloroethanol
2,2,2-Trichloroethanol
Names
IUPAC name
2,2,2-Trichloroethanol
Identifiers
 YesY
ChEBI  YesY
ChEMBL  YesY
ChemSpider  YesY
Jmol-3D images Image
KEGG  YesY
UNII  YesY
Properties
small=yes}}} }}} 0}}} 1=C|C} }}} 1=H|H} }}} 1=Ac|Ac} }}} 1=Ag|Ag} }}} 1=Al|Al} }}} 1=Am|Am} }}} 1=Ar|Ar} }}} 1=As|As} }}} 1=At|At} }}} 1=Au|Au} }}} 1=B|B} }}} 1=Ba|Ba} }}} 1=Be|Be} }}} 1=Bh|Bh} }}} 1=Bi|Bi} }}} 1=Bk|Bk} }}} 1=Br|Br} }}} 1=Ca|Ca} }}} 1=Cd|Cd} }}} 1=Ce|Ce} }}} 1=Cf|Cf} }}} 1=Cn|Cn} }}} 1=Cl|Cl} }}} 1=Cm|Cm} }}} 1=Co|Co} }}} 1=Cr|Cr} }}} 1=Cs|Cs} }}} 1=Cu|Cu} }}} 1=Db|Db} }}} 1=Ds|Ds} }}} 1=Dy|Dy} }}} 1=Er|Er} }}} 1=Es|Es} }}} 1=Eu|Eu} }}} 1=F|F} }}} 1=Fe|Fe} }}} 1=Fl|Fl} }}} 1=Fm|Fm} }}} 1=Fr|Fr} }}} 1=Ga|Ga} }}} 1=Gd|Gd} }}} 1=Ge|Ge} }}} 1=He|He} }}}}
Documentation

Density 1.55 g/cm3
Melting point 17.8 °C (64.0 °F; 291.0 K)
Boiling point 151 °C (304 °F; 424 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 YesY  (: YesY/N?)

2,2,2-Trichloroethanol is an ethanol, except the hydrogen atoms at position 2 are replaced with chlorine atoms. In humans, its pharmacological effects are similar to those of its prodrug, chloral hydrate: it is used as a sedative or a hypnotic.[1] The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.[2]

See also

References

  1. ^ The Merck Index, 13th Edition.
  2. ^




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