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Alizapride

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Title: Alizapride  
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Alizapride

Alizapride
Systematic (IUPAC) name
N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
Clinical data
AHFS/Drugs.com
Legal status
  • Prescription only
Routes Oral, IM, IV
Pharmacokinetic data
Half-life 3 hours
Excretion Renal
Identifiers
CAS number  YesY
ATC code A03
PubChem
DrugBank
ChemSpider  YesY
UNII  YesY
KEGG  YesY
ChEMBL  YesY
Chemical data
Formula C16H21N5O2 
Mol. mass 315.37 g/mol
 YesY   

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

See also

Anon., Drugs Future 1981, 6, 11.

References

  1. ^ Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M (1988). "Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial". Cancer Chemother Pharmacol 22 (4): 316–20.  



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