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Title: Anileridine  
Author: World Heritage Encyclopedia
Language: English
Subject: List of Fentanyl analogues, Acetylfentanyl, Phenoperidine, Pethidine, Fentanyl
Collection: Analgesics, Anilines, Ethyl Esters, General Anesthetics, Mu-Opioid Agonists, Piperidines, Synthetic Opioids
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
Legal status
Routes of
Tablets, injection
Pharmacokinetic data
Protein binding > 95%
Metabolism Hepatic
CAS Registry Number  Y
ATC code N01
PubChem CID:
DrugBank  Y
ChemSpider  Y
Chemical data
Formula C22H28N2O2
Molecular mass 352.47 g/mol
Physical data
Melting point 83 °C (181 °F)

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s.[1] It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.[2]


As tablets or injection.[3]


Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[4] It is mostly metabolized by the liver.


  1. ^ U.S. Patent 2,897,204
  2. ^ "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008. 
  3. ^ "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010. 
  4. ^ "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008. 

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