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Title: Bw373u86  
Author: World Heritage Encyclopedia
Language: English
Subject: Δ-opioid receptor, List of opioids, Desmethylclozapine, Zacopride, Pentylenetetrazol
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
CAS Registry Number  YesY
PubChem CID:
ChemSpider  N
Synonyms (+)BW373U86
Chemical data
Formula C27H37N3O2
Molecular mass 435.602 g/mol

(+)BW373U86 is an opioid analgesic drug used in scientific research.[1][2]

BW373U86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor.[3] It has potent analgesic and antidepressant effects in animal studies.[4][5] In studies on rats, BW373U86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). The mechanism for this is complex and may be separate from its delta agonist effects.[6][7][8]


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