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(2,2-Dimethyl-1,3-benzodioxol-4-yl) N-methylcarbamate
O=C(Oc1cccc2OC(Oc12)(C)C)NC
InChI=1S/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13) Y Key: XEGGRYVFLWGFHI-UHFFFAOYSA-N Y
InChI=1/C11H13NO4/c1-11(2)15-8-6-4-5-7(9(8)16-11)14-10(13)12-3/h4-6H,1-3H3,(H,12,13) Key: XEGGRYVFLWGFHI-UHFFFAOYAG
Bendiocarb is an acutely toxic carbamate insecticide used in public health and agriculture and is effective against a wide range of nuisance and disease vector insects. Many bendiocarb products are or were sold under the tradenames "Ficam" and "Turcam."
All bendiocarb-containing products in the malaria control.[2]
Bendiocarb is not considered to be carcinogenic, but it is acutely toxic. Like other carbamates, it reversibly inhibits acetylcholinesterase, an enzyme required for normal transmission of nerve impulses. Bendiocarb binds to the active site of this enzyme leading to an accumulation of acetylcholine, which is required for the transmission of nerve impulses, at nerve muscle sites.[1]
Bendiocarb was invented in 1971 and was first introduced into the market by Fisons Ltd. It is currently marketed by Bayer CropScience and Kuo Ching under various trade names: Ficam, Dycarb, Garvox, Turcam, Niomil, Seedox, Tattoo
Bendiocarb is highly toxic to birds and fish. In mammalian tissue, carbamates are generally excreted rapidly and do not accumulate.[1]
Note: Many of the AChE inhibitors listed above also act as BChE inhibitors.
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