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Cimoxatone

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Title: Cimoxatone  
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Subject: D-161, Sercloremine, Monoaminergic, DOV-102,677, DOV-216,303
Collection: Carbamates, Ethers, Monoamine Oxidase Inhibitors, Nitriles, Oxazolidinones, Phenol Ethers
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Cimoxatone

Cimoxatone
Systematic (IUPAC) name
3-[[4-[5-(methoxymethyl)-2-oxo-oxazolidin-3-yl]phenoxy]methyl]benzonitrile
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code None
PubChem
ChemSpider  YesY
UNII  YesY
KEGG  YesY
ChEMBL
Chemical data
Formula C19H18N2O4 
Mol. mass 338.36 g/mol
 YesY   

Cimoxatone (MD 780515) is a reversible inhibitor of MAO-A (RIMA).[1] It has a significant food interaction–related adverse effect in combination with tyramine.[2] It was never marketed.

See also

References

  1. ^ Nair NP, Ahmed SK, Kin NM, West TE (1995). "Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients". Acta Psychiatr Scand Suppl 386: 28–35.  
  2. ^ Nair NP, Ahmed SK, Kin NM (November 1993). "Biochemistry and pharmacology of reversible inhibitors of MAO-A agents: focus on moclobemide". J Psychiatry Neurosci 18 (5): 214–25.  
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