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Divaplon

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Title: Divaplon  
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Subject: Nonbenzodiazepine, Pyrazolopyrimidine, Anxiolytics, Ethers, CP-615,003
Collection: Anxiolytics, Aromatic Ketones, Ethers, Gabaa Receptor Positive Allosteric Modulators, Imidazopyrimidines
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Divaplon

Divaplon
Systematic (IUPAC) name
(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code None
PubChem
UNII  YesY
Chemical data
Formula C17H17N3O2 
Mol. mass 295.336
 YesY   

Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the pyrazolopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABAA receptor in the brain.[1][2][3]

References

  1. ^ Feely, M; Boyland, P; Picardo, A; Cox, A; Gent, JP (1989). "Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812". European Journal of Pharmacology 164 (2): 377–80.  
  2. ^ Sanger, DJ; Joly, D; Perrault, G (1995). "Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice". Psychopharmacology 121 (1): 104–8.  
  3. ^ Pellón, R; Ruíz, A; Lamas, E; Rodríguez, C (2007). "Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats". Behavioural Pharmacology 18 (1): 81–7.  
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