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Elfazepam

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Elfazepam

Elfazepam
Systematic (IUPAC) name
7-Chloro-1-(2-ethylsulfonylethyl)-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one
Clinical data
Legal status
?
Identifiers
CAS number  YesY
ATC code None
PubChem
ChemSpider  YesY
UNII  YesY
Chemical data
Formula C19H18ClFN2O3S 
Mol. mass 408.87
 YesY   

Elfazepam[1] is a drug which is a benzodiazepine derivative.[2] Presumably it has sedative and anxiolytic actions like those of other benzodiazepines.

It has appetite stimulating properties in animals.[3][4] The mechanism for increasing feed intake is not clear and has been subject of investigation.[5] It has been found that elfazepam suppresses gastric acid secretion.[6]

References

  1. ^ U.S. Patent 4,010,154
  2. ^ Psychotropics.dk
  3. ^ Baile, CA.; McLaughlin, CL. (Nov 1979). "A review of the behavioral and physiological responses to elfazepam, a chemical feed intake stimulant.". J Anim Sci 49 (5): 1371–95.  
  4. ^ Baile, CA.; Naylor, J.; McLaughlin, CL.; Catanzaro, CA. (Aug 1981). "Endotoxin-elicited fever and anorexia and elfazepam-stimulated feeding in sheep.". Physiol Behav 27 (2): 271–7.  
  5. ^ Keim, DA.; Baile, CA.; Bolton, JR.; Wangsness, PJ.; Della Fera, MA. (Jan 1979). "Abomasal function following injections of elfazepam and 9-aza-cannabinol.". Pharmacol Biochem Behav 10 (1): 63–70.  
  6. ^ Van Den Broek, GW.; Robertson, J.; Keim, DA.; Baile, CA. (Jul 1979). "Feeding and depression of abomasal secretion in sheep elicited by elfazepam and 9-aza-cannabinol.". Pharmacol Biochem Behav 11 (1): 51–6.  



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