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Esuprone

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Title: Esuprone  
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Subject: D-161, Sercloremine, Monoaminergic, DOV-102,677, DOV-216,303
Collection: Antidepressants, Coumarins, Sulfonate Esters
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Esuprone

Esuprone
Identifiers
CAS number  N
PubChem
ChemSpider  YesY
UNII  YesY
ChEMBL  YesY
Jmol-3D images Image 1
Properties[1]
Molecular formula C13H14O5S
Molar mass 282.31 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N   YesY/N?)

Esuprone is an experimental drug candidate being investigated as an antidepressant.[2] It acts as an monoamine oxidase A (MAO-A) inhibitor.[3]

References

  1. ^ Ganellin, C. R (1996). Dictionary of pharmacological agents. CRC Press. p. 1056.  
  2. ^ Vértes, Attila (2003). Handbook of nuclear chemistry. Springer. p. 155.  
  3. ^ Bergström, M; Westerberg, G; Németh, G; Traut, M; Gross, G; Greger, G; Müller-Peltzer, H; Safer, A et al. (1997). "MAO-A inhibition in brain after dosing with esuprone, moclobemide and placebo in healthy volunteers: In vivo studies with positron emission tomography". European journal of clinical pharmacology 52 (2): 121–8.  
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