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Title: Fluorolintane  
Author: World Heritage Encyclopedia
Language: English
Subject: Lefetamine, Diphenidine, Midafotel, 2,5-Dimethoxy-4-isopropylamphetamine, Macromerine
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Chemical data
Formula C18H20FN
Molecular mass 269.36 g·mol−1

Fluorolintane (also known as 2-FPPP) is a dissociative anesthetic drug that has been sold online as a designer drug.[1]

Fluorolintane and related diarylethylamines are antagonists of the NMDA receptor[2] and have been studied in vitro as potential treatments for neurotoxic injury,[3] depression[4] and as sympathomimetic.[5]

See also


  1. ^ Jason Wallach, Pierce V. Kavanagh, Gavin McLaughlin, Noreen Morris, John D. Power, Simon P. Elliott, Marion S. Mercier, David Lodge, Hamilton Morris, Nicola M. Dempster, Simon D. Brandt (May 2014). "Preparation and characterization of the ‘research chemical’ diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers". Drug Testing and Analysis 7 (5): 358–367.  
  2. ^ Michael L. Berger, Anna Schweifer, Patrick Rebernik, Friedrich Hammerschmidt (May 2009). "NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds". Bioorganic & Medicinal Chemistry 17 (1): 3456–3462.  
  3. ^ Nancy M. Gray, Brian K. Cheng. "Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury". Retrieved 17 June 2015. 
  4. ^ Brooke D Aspergren, Richard V Heinzelman (1963). "Patent US 3083139 A - Therapeutic 1-(1, 2-diphenylethyl) pyrrolidine for the management of depression". Retrieved 22 June 2015. 
  5. ^ R. V. Heinzelman , B. D. Aspergren (July 1953). "Compounds Containing the Pyrrolidine Ring. Analogs of Sympathomimetic Amines". Journal of the American Chemistry Society 75 (14): 3409–3413.  
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