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Title: Gbr-13098  
Author: World Heritage Encyclopedia
Language: English
Subject: GBR-13069, 3',4'-Methylenedioxy-α-pyrrolidinobutiophenone, 2,3-Methylenedioxyamphetamine, Dimethocaine, 2-Benzylpiperidine
Publisher: World Heritage Encyclopedia


IUPAC name
Jmol-3D images Image
Molar mass 468.56 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor.[1]

Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevented damage to the DA nerve terminals caused by malonate. It was suggested that DA transporter inhibitors like GBR-13098 could be used to prevent or treat neruodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis.[2]

See also


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