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Igh@

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Title: Igh@  
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Igh@

Immunoglobulin heavy locus
Identifiers
Symbols  ; IGH.1@; IGH@; IGHDY1
External IDs GeneCards:
Orthologs
Species Human Mouse
Entrez
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search

Immunoglobulin heavy locus, also known as IGH, is a region on human


  • Tomlinson IM, Cook GP, Walter G, et al. (1995). "A complete map of the human immunoglobulin VH locus.". Ann. N. Y. Acad. Sci. 764: 43–6.  
  • Word CJ, White MB, Kuziel WA, et al. (1991). "The human immunoglobulin C mu-C delta locus: complete nucleotide sequence and structural analysis.". Int. Immunol. 1 (3): 296–309.  
  • Buluwela L, Rabbitts TH (1989). "A VH gene is located within 95 Kb of the human immunoglobulin heavy chain constant region genes.". Eur. J. Immunol. 18 (11): 1843–5.  
  • Ichihara Y, Matsuoka H, Kurosawa Y (1989). "Organization of human immunoglobulin heavy chain diversity gene loci.". EMBO J. 7 (13): 4141–50.  
  • Ravetch JV, Siebenlist U, Korsmeyer S, et al. (1993). "Structure of the human immunoglobulin mu locus: characterization of embryonic and rearranged J and D genes.". Cell 27 (3 Pt 2): 583–91.  
  • Flanagan JG, Rabbitts TH (1983). "Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes.". Nature 300 (5894): 709–13.  
  • Mills FC, Harindranath N, Mitchell M, Max EE (1997). "Enhancer complexes located downstream of both human immunoglobulin Calpha genes.". J. Exp. Med. 186 (6): 845–58.  
  • Matsuda F, Ishii K, Bourvagnet P, et al. (1999). "The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.". J. Exp. Med. 188 (11): 2151–62.  
  • Dudley DD, Manis JP, Zarrin AA, et al. (2002). "Internal IgH class switch region deletions are position-independent and enhanced by AID expression.". Proc. Natl. Acad. Sci. U.S.A. 99 (15): 9984–9.  
  • Zhou J, Ashouian N, Delepine M, et al. (2002). "The origin of a developmentally regulated Igh replicon is located near the border of regulatory domains for Igh replication and expression.". Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13693–8.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5.  
  • Li A, Rue M, Zhou J, et al. (2004). "Utilization of Ig heavy chain variable, diversity, and joining gene segments in children with B-lineage acute lymphoblastic leukemia: implications for the mechanisms of VDJ recombination and for pathogenesis.". Blood 103 (12): 4602–9.  
  • Hallermann C, Kaune KM, Gesk S, et al. (2004). "Molecular cytogenetic analysis of chromosomal breakpoints in the IGH, MYC, BCL6, and MALT1 gene loci in primary cutaneous B-cell lymphomas.". J. Invest. Dermatol. 123 (1): 213–9.  
  • Sepulveda MA, Garrett FE, Price-Whelan A, Birshtein BK (2005). "Comparative analysis of human and mouse 3' Igh regulatory regions identifies distinctive structural features.". Mol. Immunol. 42 (5): 605–15.  
  • Streubel B, Vinatzer U, Lamprecht A, et al. (2005). "T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma.". Leukemia 19 (4): 652–8.  
  • Knezevich S, Ludkovski O, Salski C, et al. (2005). "Concurrent translocation of BCL2 and MYC with a single immunoglobulin locus in high-grade B-cell lymphomas.". Leukemia 19 (4): 659–63.  
  • Rack K, Delannoy A, Ravoet C, et al. (2005). "Translocation of BCL2 and BCL6 to the same immunoglobulin heavy chain locus in a case of follicular lymphoma.". Leuk. Lymphoma 46 (10): 1513–6.  

Further reading

  1. ^ a b "Entrez Gene: IGH immunoglobulin heavy locus". 

References

[1]

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