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Title: Miotine  
Author: World Heritage Encyclopedia
Language: English
Subject: Oxybutynin, Cholinergics, WIN-2299, Butinoline, RJR-2429
Publisher: World Heritage Encyclopedia


IUPAC name
[3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate
ChemSpider  N
Jmol-3D images Image
Molar mass 222.29 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N  (: YesY/N?)

Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]

Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]

Miotine equilibrium


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