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Sercloremine

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Sercloremine

Sercloremine
Identifiers
CAS number  YesY
PubChem
ChemSpider
Jmol-3D images Image 1
Properties
Molecular formula C14H16ClNO
Molar mass 249.74 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)

Sercloremine (CGP-4718A), usually as the hydrochloride salt, is a drug which was developed in the 1980s and was formerly under investigation as an antidepressant, but was never marketed.[1][2] It acts as a selective, reversible inhibitor of monoamine oxidase A (RIMA) and serotonin reuptake inhibitor.[1][3]

References

  1. ^ a b Barrie Hesp; Cain (2 September 1987). ANNUAL REPORTS IN MED CHEMISTRY V22 PPR. Academic Press. pp. 25–.  
  2. ^ C.R. Ganellin; David J. Triggle (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1801–.  
  3. ^ Delini-Stula, A.; Fischbach, R.; Gnirss, F.; Bures, E.; Pöldinger, W. (1985). "Early experience with CGP 4718 A (Sercloremine), a new selective and reversible MAO-A and 5-HT-uptake inhibitor, in the treatment of depressive patients". Drug Development Research 6 (4): 371–384.  



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