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Triprolidine

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Triprolidine

Triprolidine
Systematic (IUPAC) name
2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridine
Clinical data
AHFS/Drugs.com
Pregnancy
category
  • C (US)
Legal status
Routes of
administration
Oral
Pharmacokinetic data
Bioavailability 4% oral
Protein binding 90%
Metabolism Hepatic (CYP2D6)
Biological half-life 4-6 hours
Excretion Renal
Identifiers
CAS Registry Number  YesY
ATC code R06
PubChem CID:
IUPHAR/BPS
DrugBank  YesY
ChemSpider  YesY
UNII  YesY
KEGG  N
ChEBI  N
ChEMBL  YesY
Chemical data
Formula C19H22N2
Molecular mass 278.391 g/mol
Physical data
Melting point 60 °C (140 °F)
Solubility in water 500 mg/mL (20 °C)
 N   

Triprolidine (Actidil, Myidil, Actifed[In combination with pseudoephedrine, and either dextromethorphan or guaifenesin] in addition in liquids) is an over-the-counter antihistamine with anticholinergic properties.[1] It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms.[2] Like many antihistamines, the most common side effect is drowsiness.[1] Triprolidine is a quick acting drug that can clear congestion and stop runny noses in 15–30 minutes.

References

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  2. ^


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