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Vincamine

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Title: Vincamine  
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Subject: Alkaloid, Vinpocetine, ATC code C04, List of MeSH codes (D03), Vinconate
Collection: Alcohols, Carboxylate Esters, Methyl Esters, Nitrogen Heterocycles
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Vincamine

Vincamine
Systematic (IUPAC) name
(3α,14β,16α)-14,15-dihydro-
14-hydroxyeburnamenine-14-carboxylic acid methyl ester
OR
methyl (15R,17S,19R)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate
Clinical data
AHFS/Drugs.com
Identifiers
CAS Registry Number  Y
ATC code C04
PubChem CID:
IUPHAR/BPS
ChemSpider  N
UNII  Y
KEGG  Y
ChEMBL  N
Chemical data
Formula C21H26N2O3
Molecular mass 354.44 g/mol
 N   

Vincamine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the sustained release forms. Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids.[1]

Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes.

See also

References

  1. ^ "Indole Alkaloids". Ullmann's Encyclopedia of Industrial Chemistry (Fifth ed.). Wiley-VCH. 1985. p. 393.  

External links

  • "Vincamine MSDS" (pdf). 
  • Chemical Selection Working Group. "Vincamine - 1617-90-9" (pdf). Summary of Data for Chemical Selection. NIH - United States National Institutes of Health. 


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