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Plos One : Wnt Activation by Wild Type and Mutant Myocilin in Cultured Human Trabecular Meshwork Cells, Volume 7

By Linden, Rafael

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Book Id: WPLBN0003962475
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Wnt Activation by Wild Type and Mutant Myocilin in Cultured Human Trabecular Meshwork Cells, Volume 7  
Author: Linden, Rafael
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

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Linden, R. (n.d.). Plos One : Wnt Activation by Wild Type and Mutant Myocilin in Cultured Human Trabecular Meshwork Cells, Volume 7. Retrieved from http://ebook.worldlibrary.net/


Description
Description : The present study demonstrated that following forced expression of wild type myocilin, Wnt was activated, triggering in turn other myocilin-related alterations. P370L and Q368X mutations induced similar phenotypes, suggesting one possible mechanism how the mutants may lead to TM cell damage and pathology.

 

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